Production Freeze Dryer

3.24 m² shelf area, 60 kg ice capacity, PLC + HMI recipe control — commercial in-situ silicone-oil lyophilizer.

The RNE90351 is a commercial-scale in-situ silicone-oil freeze dryer for GMP production environments. With 3.24 m² of shelf area and a 60 kg condenser, it handles large peptide, biologic and small-molecule batches with the same ±1 °C uniformity as smaller LGJ models.

The RNE90351 is the largest model in the LGJ family, engineered for commercial-scale lyophilization of peptides, biologics and small-molecule APIs.

  • 3.24 m² shelf area with 6+1 shelves for commercial batch sizes
  • 60 kg / batch ice capacity and ≤ −75 °C condenser
  • Same in-situ silicone-oil thermal transfer as the LGJ-100 and LGJ-50
  • Optional water-cooled condenser for stable year-round operation
  • IQ / OQ documentation and FAT / SAT support available
ModelRNE90351
Shelf Area0.55 m²
Shelves4 + 1
Shelf Spacing80 mm
Shelf Size425 × 325 mm
Condenser Temperature≤ −75 °C
Ice Capacity≥ 10 kg / batch
Max Liquid Load5.5 L (10 mm depth)
Dimensions≈1280 × 880 × 1660 (+300) mm
CoolingAir-cooled (water-cooled option)
Control7" touch screen + PLC, multi-program
ChamberLaboratory / R&D, pilot scale

One line, five steps, zero hand-offs

Production lyophilization with full batch traceability

Recipe-controlled shelf ramping, vacuum profiling and condenser monitoring give every commercial batch a complete electronic record.

1

Loading & pre-freeze

Vials or trays are loaded and shelves ramp down to freeze the product in place.

2

Primary drying

Sublimation under ≤ 5 Pa vacuum; shelf temperature follows the programmed ramp.

3

Secondary drying

Desorption stage raises shelf temperature to strip residual moisture.

4

In-situ stoppering

Hydraulic press seats stoppers inside the chamber under vacuum or inert gas.

5

Backfill & unload

Chamber is backfilled with nitrogen and sealed vials are unloaded.

Product description

The RNE90351 is the largest model in the LGJ family, engineered for commercial-scale lyophilization of peptides, biologics and small-molecule APIs.

  • 3.24 m² shelf area with 6+1 shelves for commercial batch sizes
  • 60 kg / batch ice capacity and ≤ −75 °C condenser
  • Same in-situ silicone-oil thermal transfer as the LGJ-100 and LGJ-50
  • Optional water-cooled condenser for stable year-round operation
  • IQ / OQ documentation and FAT / SAT support available

Product related

Frequently Asked Questions (FAQs)

Please visit our FAQ page before reaching out to our customer support. Our team regularly updates this resource to provide you with the most up-to-date and comprehensive information, saving you valuable time.

Are your machines GMP-compliant?

All DIAGNOSEX process equipment is designed and manufactured in accordance with GMP / cGMP principles. Documentation packages supporting regulatory submissions — including material certificates, calibration records, and design qualifications — are available upon request.

Yes. Vial and stopper formats, throughput, automation level, cleanroom classification, and integration with upstream or downstream equipment can all be tailored to your process. Share your requirements and our engineers will propose a configuration.

Standard configurations generally ship within 8–12 weeks after order confirmation. Customized or fully integrated lines typically require 12–16 weeks, depending on the scope of engineering involved.

Yes. Our engineers provide on-site installation, commissioning, and structured operator and maintenance training. Remote commissioning support and English-language video training are also available.